RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic
methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography,
NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic
methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on
molecular biology methods.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most
highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently
consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in
print), the Series contains much material still relevant today--truly an essential publication for researchers
in all fields of life sciences.