How do you keep track of basic information on the proteins you work with? Where do you find details of their
physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary
papers and databases to locate that elusive fact?
The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate
facts about protein groups. Described as 'A growing series of excellent manuals' by Molecular Medicine Today, and
'Essential works of reference' by Trends in Biochemical Sciences the FactsBooks have become the most popular comprehensive
data resources available. Using an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest
advances in structure, amino acid sequences, physicochemical properties and biological activity. Meticulously researched
and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Leukemia-Lymphoma Cell Line FactsBook is the most comprehensive and essential reference manual for all current
well-characterised leukemia-lymphoma cell lines. Introductory chapters provide background and perspective for culturing
malignant hematopoietic cell lines. This is followed by over 400 comprehensive individual entries covering essential
clinical, immunological, genetic and functional data. Information is also provided on partly characterised leukemia-lymphoma
cell lines, growth factor-dependent cell lines, cell lines with unique chromosomal alterations, and recommended
reference cell lines.
Entries provide information on:
the full spectrum of malignant cell lines from all hematopoietic celllineages
sister cell lines and relevant subclones
clinical data: patient, diagnosis, treatment status, and specimen source
authentication of derivation and availability
immunophenotype
cytogenetic karyotype
translocations and fusion genes
receptor gene rearrangements and genetic alterations
cell cultures aspects: establishment, medium, doubling time, growth
cytochemical profile
cytokine production and response to cytokines
proto-oncogene and transcription factor expression/alteration
