This introductory textbook explores bacterial disease mechanisms and bacteria-host interactions. The central
premise is that bacteria have evolved by means of manipulating normal host cell functions and overcoming host defense
systems to ensure their survival. As well as offering a new perspective on the classical bacterial virulence mechanisms,
this book outlines the new molecular techniques developed to unravel the complexity of bacteria-host interactions.
Current research may lead not only to a better understanding of disease mechanisms, but also to new means of preventing
and/or treating bacterial infections.
Table of Contents
Preface
1. An introduction to bacterial diseases
2. Bacterial cell biology
3. Molecular analysis of bacterial disease mechanisms
4. Communication in infection
5. The mucosal surface: the front line of anti-bacterial defence
6. Immune defences against bacteria
7. Bacterial adhesion as a virulence mechanism
8. Bacterial invasion as a virulence mechanism
9. Bacterial exotoxins
10. Bacterial evasion of host defence mechanisms
11. Bacteria in human health and disease: the future?
